antimicrobial susceptibility and clonal relation between acinetobacter baumannii strains at a tertiary care center in turkey

نویسندگان

gulfem ece department of medical microbiology, school of medicine, izmir university, izmir, turkey; department of medical microbiology, medicalpark hospital, school of medicine, izmir university, yeni girne boulevard, 1825th st., no 12, karsıyaka, izmir, turkey. tel: +90-2323995050

bayri erac department of pharmaceutical microbiology, school of pharmacy, ege university, izmir, turkey

hasan yurday cetin department of anesthesiology and reanimation, school of medicine, izmir university, izmir, turkey

cem ece department of anesthesiology and reanimation, menemen state hospital, izmir, turkey

چکیده

background acinetobacter baumannii is an opportunistic pathogen, related with nosocomial infections such as bacteremia, urinary tract infections, and ventilator-associated pneumonia. multidrug resistant (mdr) a. baumannii strains are first line causes of infection, especially in patients hospitalized at intensive care units (icus). infection with mdr a. baumannii strains has a longer duration at icus and hospitals. there are studies using molecular methods which can differentiate mdr a. baumannii strains at the clonal level. this helps controlling these resistant strains and prevents their epidemy. objectives the aim of our study was to investigate the antimicrobial susceptibility and clonal relationship between the a. baumannii strains isolated from our icu. materials and methods the identification and antimicrobial susceptibility of 33 a. baumannii strains were performed by automatized vitek version 2.0. the clonal relationship among a. baumannii strains was analyzed using enterobacterial repetitive intergenic consensus (eric) polymerase chain reaction (pcr). results a total of 33 a. baumannii strains were included in this study. a. baumannii complex strains were classified into seven clusters based on the fingerprint results. our results revealed that two main clusters were responsible for the prevalence of a. baumannii complex strains at the icu. conclusions mdr a. baumannii strains cause an increment in morbidity and mortality, particularly in icus. the use of molecular epidemiological methods can help us with the detection of the pathogen and preventing from spreading of these resistant strains.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antimicrobial Susceptibility and Clonal Relation Between Acinetobacter baumannii Strains at a Tertiary Care Center in Turkey

BACKGROUND Acinetobacter baumannii is an opportunistic pathogen, related with nosocomial infections such as bacteremia, urinary tract infections, and ventilator-associated pneumonia. Multidrug resistant (MDR) A. baumannii strains are first line causes of infection, especially in patients hospitalized at intensive care units (ICUs). Infection with MDR A. baumannii strains has a longer duration a...

متن کامل

A. baumannii, Infection Rate and Antimicrobial Susceptibility in an Iranian Tertiary Care Hospital

Background and Objectives: A. baumannii is a cause of various infections with significant morbidity and mortality in the world. The aim of this study was to determine infection rate and antimicrobial susceptibility of A. baumannii in an Iranian tertiary care Hospital.   Materials and Methods:  This study was performed on 166 positive blood cultures for A. baumannii,</em...

متن کامل

Ventilator Associated Pneumonia by Acinetobacter baumannii And antimicrobial susceptibility pattern

Background: Ventilator Associated Pneumonia (VAP) is one of the serious complications of ventilator support occurring in ICUs. The aim of this study was to determine the susceptibility pattern of Acinetobacter baumannii (A. baumannii) isolated from patients with VAP by two methods: disk diffusion and E. test. Methods: This descriptive-cross sectional study was conducted in the four ICUs of Ras...

متن کامل

Evaluation of the in vitro colistin susceptibility of Pseudomonas aeruginosa and Acinetobacter baumannii strains at a tertiary care centre in Western Turkey.

Multidrug-resistant gram-negative bacteria are an important issue in intensive care units worldwide. Colistin, one of the earliest polymyxin antibiotics, was once widely used for the treatment of gram-negative bacterial infections. However, its use is now limited due to concerns over nephrotoxicity. The appearance of multidrug-resistant species, including A. baumannii and P. aeruginosa, has led...

متن کامل

Antimicrobial Resistance Pattern of Acinetobacter baumannii Strains Isolated from Intensive Care Unit Patients

ABSTRACT             Background and Objectives: Acinetobacter baumannii is an opportunistic pathogen that affects different groups of people, especially intensive care unit (ICU) patients. The prevalence of infections caused by this bacterium is very high. Today, prevalence of infections caused by multidrug-resistant (MDR) and extreme-drug resistant (XDR) strains is increasing. This study aime...

متن کامل

a. baumannii, infection rate and antimicrobial susceptibility in an iranian tertiary care hospital

background and objectives: a. baumannii is a cause of various infections with significant morbidity and mortality in the world. the aim of this study was to determine infection rate and antimicrobial susceptibility of a. baumannii in an iranian tertiary care hospital.   materials and methods:  this study was performed on 166 positive blood cultures for a. baumannii, received from different w...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
jundishapur journal of microbiology

جلد ۸، شماره ۲، صفحات ۰-۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023